Overview:

Testosurge® is a natural, highly standardized ingredient proven in clinical studies to significantly increase total and biologically active free testosterone. Designed for products to boost testosterone, increase performance, and support healthy sexual function.

Claims researched:

Based upon the current information available Testosurge™ qualifies for our STRONGSCIENCE® Certification Mark for the following composite claims:

1. Helps promote/support testosterone production in men
2. Supports total/free/bioavailable testosterone production
3. Increases total, bioavailable and free testosterone levels in men
4. Increases plasma free/total plasma/bioavailable plasma testosterone levels
5. Acutely increases testosterone levels[1]
6. Aromatase & 5-alpha reductase inhibitor
7. Increases androgen status
8. May help support sexual health in men
9. Helps support normal levels of free testosterone in men
10. Supports healthy testosterone levels that may decline with age

¹ 600 mg dose once per day

Ingredient List:

 Active Ingredients: Testosurge™ (Trigonella foenum-graecum L.) – Standardized to ³ 80% Glycosides (Grecunin™)

RESEARCH TRANSPARENCY™ (Reference List)

 TESTOSURGE®

1. https://naturalmedicines.therapeuticresearch.com/search.aspx?q=fenugreek&go.x=0&go.y=0
2. Ouzir M, El Bairi K, Amzazi S. Toxicological properties of fenugreek (Trigonella foenum graecum). Food Chem Toxicol. 2016 Oct;96:145-54. View abstract.
3. Sowmya P, Rajyalakshmi P. Hypocholesterolemic effect of germinated fenugreek seeds in human subjects. Plant Foods Hum Nutr 1999;53:359-65.
4. Duke’s Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
5. Flammang AM, Cifone MA, Erexson GL, Stankowski LF Jr. Genotoxicity testing of a fenugreek extract. Food Chem Toxicol 2004;42:1769-75. View abstract.
6. Zhao, H. Q., Qu, Y., Wang, X. Y., Zhang, H. J., Li, F. M., and Masao, H. [Determination of trigonelline in Trigonella foenum-graecum by HPLC]. Zhongguo Zhong.Yao Za Zhi. 2002;27(3):194-196. View abstract.
7. Taylor, W. G., Zulyniak, H. J., Richards, K. W., Acharya, S. N., Bittman, S., and Elder, J. L. Variation in diosgenin levels among 10 accessions of fenugreek seeds produced in western Canada. J Agric.Food Chem 10-9-2002;50(21):5994-5997. View abstract.
8. Trivedi, P. D., Pundarikakshudu, K., Rathnam, S., and Shah, K. S. A validated quantitative thin-layer chromatographic method for estimation of diosgenin in various plant samples, extract, and market formulation. J AOAC Int 2007;90(2):358-363. View abstract.
9. Hibasami, H., Moteki, H., Ishikawa, K., Katsuzaki, H., Imai, K., Yoshioka, K., Ishii, Y., and Komiya, T. Protodioscin isolated from fenugreek (Trigonella foenumgraecum L.) induces cell death and morphological change indicative of apoptosis in leukemic cell line H-60, but not in gastric cancer cell line KATO III. Int J Mol.Med 2003;11(1):23-26. View abstract.
10. Murakami, T., Kishi, A., Matsuda, H., and Yoshikawa, M. Medicinal foodstuffs. XVII. Fenugreek seed. (3): structures of new furostanol-type steroid saponins, trigoneosides Xa, Xb, XIb, XIIa, XIIb, and XIIIa, from the seeds of Egyptian Trigonellafoenum-graecum L. Chem Pharm.Bull (Tokyo) 2000;48(7):994-1000. View abstract.
11. Daoud, K. M. The reserve polysaccharide of the seeds of fenugreek: its digestibility and its fate during germination. Biochem.J 1932;26(1):255-263. View abstract.
12. Roberts, K. T. The potential of fenugreek (Trigonella foenum-graecum) as a functional food and nutraceutical and its effects on glycemia and lipidemia. J Med.Food 2011;14(12):1485-1489. View abstract.
13. Awadalla, M. Z., El Gedaily, A. M., El Shamy, A. E., and El Aziz, K. A. Studies on some Egyptian foods. Part 1: Biochemical and biological evaluation. Z. Ernahrungswiss. 1980;19(4):244-247. View abstract.
14. Al-khalisy MHH. Treatment of Men Infertility using Low doses of Fenugreek Oil Extract. Advances Life Sci Technol 2015;29:13-16.
15. Wilborn C, Taylor L, Poole C, Foster C, Willoughby D, Kreider R. Effects of a purported aromatase and 5alpha-reductase inhibitor on hormone profiles in college-age men. Int J Sport Nutr Exerc Metab. 2010;20(6):457-65.
16. Rao et al. 2016. Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomized clinical study. Aging Male. 2016 Jun;19(2):134-42. doi: 10.3109/13685538.2015.1135323
17. Wankhede S, Mohan V, Thakurdesai P. 2016. Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: a randomized controlled pilot study, Journal of Sport and Health Science. 2015, doi: 10.1016/j.jshs.2014.09.005.
18. Arafa MH, Mohammad NS, Atteia HH. Fenugreek seed powder mitigates cadmium-induced testicular damage and hepatotoxicity in male rats. Exp Toxicol Pathol. 2014 Sep;66(7):293-300. View abstract.
19. Hamden K, Jaouadi B, Carreau S, Aouidet A, El-Fazaa S, Gharbi N, Elfeki A. Potential protective effect on key steroidogenesis and metabolic enzymes and sperm abnormalities by fenugreek steroids in testis and epididymis of surviving diabetic rats. Arch Physiol Biochem. 2010 Jul;116(3):146-55. View abstract.
20. Urmila Aswar et.al, 2010. Effect of Furostanol Glycosides from Trigonella foenum –graecum on the reproductive system of Male Albino Rats. Phytotherapy Research, 24, 1482–1488
21. Steels, E., Rao, A. and Vitetta, L., 2011. Physiological Aspects of Male Libido Enhanced by Standardized Trigonella foenum-graecum Extract and Mineral Formulation. Phytotherapy Research, Vol. 25, 1294–1300. doi: 10.1002/ptr.3360
22. Rao A, Steels E, Beccaria G, Inder WJ, Vitetta L. Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Phytother Res. 2015 Aug;29(8):1123-30. View abstract.
23. Mokashi et al. (2014). Effects of glycosides-based fenugreek seed extract on serum testosterone levels of healthy sedentary male subjects: an exploratory double blind, placebo-controlled, crossover study. Asian J of Pharmaceutical and Clinical Research. 7(2):177-181.
24. Willoughby, D.S., Wilborn, C., Taylor, L., & Campbell, W. (2007). Eight weeks of aromatase inhibition using the nutritional supplement Novedex XT: Effects in young, eugonadal men. International Journal of Sport Nutrition and Exercise Metabolism, 17(1), 92–108.
25. Rohle, D., Wilborn, C., Taylor, L., Mulligan, C., Kreider,, & Willoughby, D. (2007). Effects of eight weeks ofan alleged aromatase inhibiting nutritional supplement6-OXO (androst-4-ene-3,6,17-trione) on serum hormoneprofiles and clinical safety markers in resistance-trained,eugonadal males. Journal of the International Society of Sports Nutrition, 4(13).
26. Swaroop A, Jaipuriar AS, Gupta SK, Bagchi M, Kumar P, Preuss HG, Bagchi D. Efficacy of a Novel Fenugreek Seed Extract (Trigonella foenum-graecum, Furocyst) in Polycystic Ovary Syndrome (PCOS). Int J Med Sci. 2015 Oct 3;12(10):825-31
27. Wilborn C, Bushey B, Poole C, et al. Effects of Torabolic supplementation on strength and body composition during an 8-week resistance training program. J Int Soc Sports Nutr 2008;5(1):11.
28. Ruby, B. C., Gaskill, S. E., Slivka, D., and Harger, S. G. The addition of fenugreek extract (Trigonella foenum-graecum) to glucose feeding increases muscle glycogen resynthesis after exercise. Amino.Acids 2005;28(1):71-76. View abstract.
29. Slivka, D., Cuddy, J., Hailes, W., Harger, S., and Ruby, B. Glycogen resynthesis and exercise performance with the addition of fenugreek extract (4-hydroxyisoleucine) to post-exercise carbohydrate feeding. Amino.Acids 2008;35(2):439-444. View abstract.
30. Ikeuchi M, Yamaguchi K, Koyama T, Sono Y, Yazawa K. Effects of fenugreek seeds (Trigonella foenum greaecum) extract on endurance capacity in mice. J Nutr Sci Vitaminol (Tokyo). 2006;52(4):287-92.
31. Health Canada Licensed Natural Health Products Database (LNHPD) – Testosurge/Andropiquehttps://health-products.canada.ca/lnhpd-bdpsnh/info.do?licence=80070705
32. Health Canada Licensed Natural Health Products Database (LNHPD) – Andropique Elite

https://health-products.canada.ca/lnhpd-bdpsnh/info.do?licence=80085896

33. Health Canada Licensed Natural Health Products Database (LNHPD) – Andropique Premium

https://health-products.canada.ca/lnhpd-bdpsnh/info.do?licence=80092221

34. Mansooriet 2020.  Effect of fenugreek extract supplement on testosterone levels in male: A meta-analysis of clinical trials. Phytother Res. 34(7):1550-1555.
35. Poole C, Bushey B, Foster C, Campbell B, Willoughby D, Kreider R, et al. The effects of a commercially available botanical supplement on strength, body composition, power output, and hormonal profiles in resistance-trained males. J Int Soc Sports Nutr. 2010;7:34.
36. Taylor et al. 2009. Fenugreek Extract Supplementation Has No Effect on The Hormonal Profile Of Resistance-trained Males. Med Sci Sports Exer. 2(1): S13 Bushney et al.. IJESAB 2  Iss. 1 (2009)
37. Maheshwari et al. 2017.Efficacy of FurosapTM, a novel Trigonella foenum-graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers. Int J Med Sci. 14(10):58-66
38. Deshpande P, Mohan V, Ingavale D, Mane J, Pore M, Thakurdesai PhD P. 2017. Preclinical Safety Assessment of Furostanol Glycoside-based Standardized Fenugreek Extract in Rats. J Diet Suppl.3;14(5):521-541. doi: 10.1080/19390211.2016.1272659. Epub 2017 Feb 3.
39. Thakurdesai PA, Mohan V, Bhaskaran S. Toxicological evaluation of flavonoid glycosides based standardized fenugreek seed extract [TOX/PP- 15]. In: 46th Annual Conference of Indian Pharmacological Society and International Conference on Translational Medicine, 16^th– 18th December 2013. Bangalore: Indian Pharmacological Society; 2013.
40. Deshpande et al. 2017. Prenatal Developmental Toxicity Study of Glycosides-based Standardized Fenugreek Seed Extract in Rats. Pharmacogn Mag. 2017 Jan; 13(Suppl 1): S135–S141
41. Basch E, Ulbricht C, Kuo G, Szapary P, Smith M. Therapeutic applications of fenugreek. Altern Med Rev. 2003;8(1):20-7.
42. Thompson Coon JS, Ernst E. Herbs for serum cholesterol reduction: a systematic view. J Fam Pract. 2003;52(6):468-78.
43. Poole et al. 2009. Effects of Testosurge Supplementation on Strength, Body Composition and Hormonal Profiles during an 8-Week Resistance Training Program. JISSN. 6(Suppl1): P12
44. Electronic Code of Federal Regulations. Title 21. Part 182 — Substances Generally Recognized As Safe. Available at: accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=182.20
45. Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. View abstract.
46. Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8. View abstract.
47. Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9.
48. Reeder C, Legrand A, O’Connor-Von SK. The Effect of Fenugreek on Milk Production and Prolactin Levels in Mothers of Preterm Infants. Clinical Lactation 2013;4(4):159-165.

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